Bullous Lesions
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Bullous lesions
      Subcorneal
              Acantholysis
                      Pemphigus foliaceus
                              Not inflammed
                     Bullous Impetigo
                              Neutrophils
             No Acantholysis
                      Scabies
      Intraepidermal        
             Acantholysis
                      Pemphigus Vulgaris
                              Anti-desmoglian 3
                             Row of tombstones
                     PemphigusVegetans
                              Supra basal separation
                     Hailey Hailey
                              AKA Benign familial pemphigus
                             AD inheritance
                             Histology Like Pemphigus Vulgaris
                     Darier disease
                              AKA keratosis follicularis
                             AD inheritance
                             Suprabasal acantholytic vesicles w/ “grains”
                             Dermal papillae w/ single layer keratinocytes
                     Grover disease
                              Related to heat and sweat
                             Histology like Darier disease
                     Warty Dyskeratoma
                              Histology like Darier disease
                             On Sun exposed areas
                     Herpes
              No Acantholysis
                      Erythema Toxicum neonatorum
                              Eosinophils
                     Dermatophytes
                     Spongiotic dermatitis
      Subepidermal
              Inflammed
                      Bullous pemphigoid
                              Anti-desmosomal proteins
                     Dermatitis Herpatiformis
                              Assoc. w/ gluten enteropathy
                             Hypersensitivity to gliadin
                             Micro abscesses @ tip of dermal papillae
                             IgA / IgG deposits
             No Inflammation
                      Epidermolysis bullosa
                     Porphyria Cutanea tarda